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Mitragynine itself acts primarily via μ-opioid receptors, though its oxidation product mitragynine-pseudoindoxyl, acts as an even more potent and selective μ-opioid agonist with less affinity for δ or κ receptors.Another alkaloid with a major contribution to the μ-opioid activity of the kratom plant is the related compound 7-hydroxymitragynine, which while present in the plant in much smaller quantities than mitragynine, is a much more potent μ-opioid agonist.
|Synonyms||9-methoxy Corynantheidine Kratom|
|IUPAC||3-ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-methyl ester, (αE,2S,3S,12bS)-indolo[2,3-a]quinolizine-2-acetic acid|