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Andarine (S-4)

Selective Androgen Receptor Modulator

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Product Description
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Tired of testosterone, prohormones and other compounds that don’t give you the best results? try S-4 Andarine!



WHAT IS S-4 ANDARINE?

S-4 Andarine is a Selective androgen receptor modulator (SARM). Apart from having similar effects to traditional anabolic steroids, S-4 has the advantage of not having androgenic activity in non-skeletal muscle and other tissues where they should not interfere.

S-4 Andarine is an oral SARM.

If you want more information on SARMs in general, you can find it HERE and learn all you need to know, from their history, benefits and how do they work.

 

Is there any evidence for S-4 claims?

Off course there is! Studies have shown that 3 mg/kg/day were able to restore skeletal muscle and strength in lab rats that had been previously castrated. Other than medical uses for treatment, S-4 Has several uses.

Lose bodyfat:

Losing Bodyfat is where S-4 Shines above all else. Some steroids like winstrol and anavar are considered “cutting” steroids, and they are very good at this, however, these don’t offer too much in muscle mass gain; S-4 is similar in many aspects.

Because of the presence of certain receptors in bodyfat cells (preadipocytes and adipocytes), researches have suggested that androgens might be able to not only accelerate the bodyfat losing speed, but also regulate its development altogether [Kearbey et al., 2007].

Studies have also suggested that S-4 decrease Lipoprotein lipase, an enzyme which causes fat accumulation.

Because S-4 has anabolic and androgenic effects in muscle tissue, it will help with fat loss, but also maintain and even boost muscle mass when cutting. An added bonus is that S-4 increases vascularization, which induces a nice natural, hard look to the user’s muscle with almost 0 water retention. Because of this, S-4 could be compared to Winstrol, however, this SARM does not produce the harsh hair loss and cholesterol build up. Furthermore, Winstrol and other popular cutting steroids and prohormones usually have a drying effect on the athlete’s joints, S-4 does not suffer from this side effect, so the user can conformably keep lifting in order to maintain or increase muscle mass and strength [Chen et al., 2005; Gao et al., 2005; Kearbey et al., 2007].

 

Also, another thing S-4 offers for cutting is that it doesn’t give the painful pumps associated with other popular steroids/Prohormones. Back and calf pumps are particularly bad for cutting as it halts the ability to perform cardio.

 

Dosage:

Most users however, flock to S-4 for its amazing recomping effect of losing fat at the same time you gain muscle. Trying to achieve this when you’re not totally new to training is extremely hard. Because S-4 is taken orally and it’s not liver toxic, you can run it for over 6 weeks with no trouble.

For this recomping effects, you’d need to take between 50 to 75 milligrams for 4 to 8 weeks, however, diet must also be optimized to barely above maintenance calorie levels, and 30% of that coming from lean sources.

For cutting purposes, a dosage protocol of 50 mg for 6 to 8 weeks is ideal for most scenarios and users.

 

Caution ensues:

Although S-4 negates plenty of serious side effects, there is one caution to take…
With dosages of 50 mg and up, a continued use can cause vision disturbances, however, a 5 days on, 2 off and repeat for the whole period will most often stop this side effect from happening. If this ever happens, discontinuing S-4 usage will soon enough make the symptoms go away.

 

What we got until now?

  • Anabolic without major side effects
  • Great for strength
  • Great for muscle hardness
  • Great for enhanced vascularity
  • Great for endurance (aerobic or anaerobic)
  • Accelerated fat loss above 50mg



Are you looking for something to give you that muscle boost while losing undesirable fat? Well, this is the product for you, seems like magic, doesn’t it? Well, it is not, it’s called chemistry, and it now brings you this amazing compound that will allow you to get your desired goals without negative side effects like mentioned.



Application Selective Androgen Receptor Modulator
CAS 401900-40-1
Molar Mass 441.357 g/mol
 Chemical Formula C19H18F3N3O6
Chemical Name (2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
Synonyms Andarine, Andarin, S-4, S-40503, GTx-007
Storage Room temperature
Solubility Ethanol, DMSO
Organoleptic Profile Pale yellow fine powder, odorless, acrid bitter taste
Physical Form Solid, powder

Sources:

[WebPages]

http://www.nature.com/nchembio/journal/v4/n10/full/nchembio1008-583.html

https://www.muscle-research.com/content/1216-S4-(Andarine)

https://proteinfactory.com/andarine/

https://www.reddit.com/r/PEDs/comments/2yzkev/ostarine_mk2866_vs_andarine_s4_vs_ligandrol/

[Research Papers] 

  Selective androgen receptor modulator treatment improves muscle strength and body composition and prevents bone loss in orchidectomized rats. (2005). Retrieved June 5th, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/16099859

    Narayanan, R., Mohler, M. L., Bohl, C. E., Miller, D. D., & Dalton, J. T. (2008). Selective androgen receptor modulators in preclinical and clinical development. Retrieved June 5th, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602589/

   Dayger, C., Villasana, L., Pfankuch, T., Davis, M., & Raber, J. (2011). Effects of the SARM ACP-105 on rotorod performance and cued fear conditioning in sham-irradiated and irradiated female mice. Retrieved June 5th, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048897/

   Effects of selective androgen receptor modulator (SARM) treatment in osteopenic female rats. (2009). Retrieved June 5th, 2017, from https://www.ncbi.nlm.nih.gov/pubmed/19728047

 Otto-Duessel, M., He, M., Adamson, T. W., & Jones, J. O. (2013). Enhanced Evaluation of Selective Androgen Receptor Modulators In Vivo. Retrieved June 5th, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910424/

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